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Role of acetylation in doxorubicin-induced cardiotoxicity

Moreover, older people tend to exhibit a decrease in intestinal absorption and utilization of vitamins, an example being the reduced gastric acid secretion potentially causing vitamin B 12 deficiency or the inhibited subcutaneous vitamin D synthesis (75% reduction of vitamin D synthesis in people aged 65 [54] in addition to a lowered renal conversion of 25-hydroxycholecalciferol (calcifediol) to the active 1,25-dihydroxycholecalciferol (calcitriol) [55, 56]

Woodruff, P

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